Daxxify (daxibotulinumtoxinA) Cost (2026)
Daxxify (daxibotulinumtoxinA) costs $480 - $850 nationally in 2026, with a median of $600. Pricing varies significantly by metro market, provider credentials, and case complexity.
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About Daxxify (daxibotulinumtoxinA)
Daxxify (daxibotulinumtoxinA from Revance Aesthetics) is the newest FDA-approved botulinum toxin in the US market (approved 2022). The product uses a peptide excipient instead of human serum albumin, and clinical trials demonstrated 6-month median duration vs the 3-4 months typical for Botox, Dysport, and Xeomin. Adoption growing in 2026 driven by patients wanting fewer injections per year. Average $16-$22 per unit ($480-$660 per glabellar treatment).
What it is
Injectable daxibotulinumtoxinA at 20 units glabellar dose (1:1 with Botox dosing for cosmetic use). Mechanism identical to other botulinum toxins: blocks neuromuscular signaling at the injection site. Unique peptide-stabilized formulation produces longer duration.
Who it is for
Adults seeking neuromodulator treatment for dynamic facial wrinkles (glabellar, forehead, crows feet) who want fewer treatments per year. Premium-priced; appropriate when 2x/year treatment cadence is preferred over 3-4x/year with other neuromodulators.
What is typically included
- Consultation
- 20 unit glabellar treatment
- Post-treatment care
Procedure snapshot
- Category
- Injectables
- Timeline
- 1 day
- Typical recovery
- 0 days
- Financing common
- No
- Evidence level
- FDA-Approved
Cost factors
Units used
Glabellar: 20 units. Forehead: 10-20 units. Crows feet: 24 units (12 each side). Full face: 40-60 units total.
Provider type
Dermatology or plastic surgery practices charge premium over medical spas.
Daxxify rewards program
Revance has a loyalty program offering discounts on repeat treatments.
Daxxify (daxibotulinumtoxinA) Cost by City
Median daxxify (daxibotulinumtoxina) pricing across top US metros.
Frequently asked questions
How much does Daxxify cost in 2026? +
Per unit: $16-$22 in US. Glabellar treatment (20 units): $480-$660. Full face (forehead + glabellar + crows feet, 40-60 units): $720-$1,200. Daxxify is premium-priced vs Botox ($14-$20/unit) reflecting the longer duration.
Does Daxxify really last 6 months? +
Clinical trials showed median duration of 6 months at the glabellar site (vs 3-4 months for other neuromodulators). Individual patient duration varies: some patients see 6+ months, others see closer to 4-5 months. Real-world median in 2026 is approximately 4-5 months at glabellar, slightly shorter at other facial sites.
Daxxify vs Botox? +
Daxxify: 6-month median duration in trials, $16-$22/unit, peptide excipient. Botox: 3-4 month duration, $14-$20/unit, human serum albumin excipient. For patients wanting fewer treatments per year and budget tolerates premium, Daxxify is the practical choice. For cost-conscious patients comfortable with 3-4x annual treatments, Botox remains the value option.
Is Daxxify safer than Botox? +
Safety profiles are comparable. Both are FDA-approved with established clinical use. Daxxify is newer with less long-term human use data; Botox has 23+ years of cosmetic use. Common side effects (bruising, headache, eyelid heaviness) similar across all neuromodulators.
Will Daxxify work for migraines like Botox? +
Daxxify is FDA-approved for cosmetic glabellar lines only. Botox is FDA-approved for chronic migraine. Off-label Daxxify use for migraines exists but most migraine prescribers stick with Botox where insurance coverage is established.
Sources
- FDA Daxxify Prescribing Information, current 2026 label. (Indication and dosing)
- Carruthers J et al. SAKURA Trials of Daxibotulinumtoxin A. JAMA Dermatol, 2024. (Duration evidence)